proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus
نویسندگان
چکیده
منابع مشابه
synaptic neuronal plasticity
context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...
متن کاملThe effect of ketamine on synaptic transmission and synaptic plasticity in CA1 area of rat hippocampal slices
The effect of ketamine (1-100 µM), which has NMDA receptor antagonist properties, on synaptic transmission and long-term potentiation (LTP) in CAl area of rat hippocampus was examined in vitro. Field potentials were recorded in pyramidal cell layer following Schaffer collateral stimulation. Primed-burst stimulation (PEs) was used for induction of LTP. The amplitude of population spiks (PS) was ...
متن کاملBAI1 regulates spatial learning and synaptic plasticity in the hippocampus.
Synaptic plasticity is the ability of synapses to modulate the strength of neuronal connections; however, the molecular factors that regulate this feature are incompletely understood. Here, we demonstrated that mice lacking brain-specific angiogenesis inhibitor 1 (BAI1) have severe deficits in hippocampus-dependent spatial learning and memory that are accompanied by enhanced long-term potentiat...
متن کاملProgesterone regulation of synaptic transmission and plasticity in rodent hippocampus.
Ovarian hormones influence memory formation by eliciting changes in neural activity. The effects of various concentrations of progesterone (P4) on synaptic transmission and plasticity associated with long-term potentiation (LTP) and long-term depression (LTD) were studied using in vitro hippocampal slices. Extracellular studies show that the highest concentration of P4 tested (10(-6) M) decreas...
متن کاملfor synaptic transmission and plasticity in the hippocampus
Presentation Title: Early ablation of mGluR5 receptor affects the maturation of parvalbumin interneurons: Consequences for synaptic transmission and plasticity in the hippocampus Location: Halls B-H Abstract: Fast spiking (FS) interneurons play an important role in controlling the activity of pyramidal cells by providing them with strong perisomatic inhibitory inputs. The dysfunction of FS cell...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Reports
سال: 2014
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2014.03.040